5: 6-DITHIADECAMETHYLENE 1:10-BIS(TRIMETHYL-AMMONIUM IODIDE): A NEW MYONEURAL BLOCKING AGENT OF THE DEPOLARIZING TYPE
نویسندگان
چکیده
منابع مشابه
the investigation of the relationship between type a and type b personalities and quality of translation
چکیده ندارد.
The classification of the myoneural blocking agents.
THE classification of myoneural blocking agents at present accepted at least in Great Britain, divides these drugs into two groups, viz. those which compete with acetylcholine and prevent its access to the muscle end plate, i.e. the competitive blockers, and those which themselves depolarize the end plate with the result that the normal depolarizer, acetylcholine, is no longer able to exert its...
متن کاملStudies on fazadinium bromide (ah 8165): a new non-depolarizing neuromuscular blocking agent.
Intravenous dose-response relationships were used to correlate neuromuscular paralysis with the effects of fazadinium (AH 8165) on autonomic mechanisms in anaesthetized cats and rhesus monkeys and with cardiovascular effects in man. In cats and monkeys neuromuscular paralysis of the twitch responses of the gastrocnemius muscle by fazadinium was accompanied by impairment of the vagally induced b...
متن کاملThe pharmacological actions of polymethylene bistrimethyl-ammonium salts.
Since the classical work of Crum Brown and Fraser, the curariform action of many onium salts has been recognized, and other activities exerted by these compounds have been described, such as those commonly called nicotine-like or muscarine-like. In the present paper an account is given of the actions of members of a polymethylene bistrimethylammonium series, whose general formula is (CH,), N+(C...
متن کاملBis(triphenylphosphoranylidene)ammonium iodide
The title compound, C(36)H(30)NP(2) (+)·I(-), was obtained accidently from crystallization of a reaction mixture containing [(Ph(3)P)(2)N]OH and B(OH)(3), which was contaminated with MeI. There are two independent [(Ph(3)P)(2)N](+) cations and two I(-) anions within the asymmetric unit. The central PNP angles are non-linear [137.6 (2) and 134.4 (2)°] and the phenyl substituents on P centres ado...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology and Chemotherapy
سال: 1953
ISSN: 0366-0826
DOI: 10.1111/j.1476-5381.1953.tb00762.x